منابع مشابه
Treatment of non-Hodgkin's lymphoma (NHL) with radiolabeled antibodies (mAbs).
Most patients with non-Hodgkin's lymphoma (NHL) achieve remission but, despite newer drugs, the natural history of this disease has not improved during the last 20 years. Less than one half of patients with aggressive NHL are cured, and few of those with low-grade NHL are curable. Furthermore, NHL becomes progressively more chemoresistant while remaining responsive to external beam radiation th...
متن کاملFollicular NHL: from antibodies and vaccines to graft-versus-lymphoma effects.
Monoclonal antibody therapy with rituximab in combination with standard chemotherapy has improved the survival of patients with advanced-stage follicular lymphoma (FL). A series of next-generation anti-CD20 antibodies may be less immunogenic and have even greater antitumor activity through augmented interactions with host effector mechanisms responsible for tumor cell kill. Additional approache...
متن کاملCombining organic acid treatment with steam pasteurization to eliminate Listeria monocytogenes on fully cooked frankfurters.
An organic acid solution of 2% acetic, 1% lactic, 0.1% propionic, and 0.1% benzoic acids was combined with steam surface pasteurization to treat frankfurters during vacuum packaging to eliminate potential postcook contamination with Listeria monocytogenes. The thermal lethality of L. monocytogenes from steam was evaluated at an inoculation concentration of 1 to 6 log CFU/cm2. About 3-log reduct...
متن کاملCombining site specificities of mouse hybridoma antibodies to dextran B1355S
The combining sites of 12 mouse hybridoma antibodies to dextran B1355S have been characterized by quantitative precipitin assay. All antibodies preferentially bind the immunizing antigen B1355S and two other class I dextrans, B1498S and B1501S, but show substantial differences in the extents to which they cross react with class I dextrans, suggesting their clustering into five groups. Three mye...
متن کاملA radical approach is needed to eliminate interference from endogenous antibodies in immunoassays.
Interference in immunoassays by circulating endogenous antibodies is as old as the technique itself. Its mechanisms have remained poorly studied, however, and its detrimental effects are underestimated despite numerous reports highlighting its serious consequences (1–9). One reason for this situation is that immunoassays are moving targets. Assay protocols and reagents, even from the same provi...
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ژورنال
عنوان ژورنال: Science-Business eXchange
سال: 2010
ISSN: 1945-3477
DOI: 10.1038/scibx.2010.1109